Diners typically serve staples of American cuisine such as hamburgers, french fries, onion rings, club sandwiches, and other simple, quickly cooked, and inexpensive fare, such as meatloaf or steak. Much of the food is grilled, as early diners were based around a gas-fueled flattop grill. Coffee is a diner staple.

Many quintessential American dishes are unique takes on food originally from other culinary traditions, including pizza, hot dogs, and Tex-Mex. Regional highlights include a range of fish dishes in the coastal states, gumbo, and cheesesteak.